Article
Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients.
Scientific reports - 15 Aug 2017
Al-Daghri Nasser M, Mohammed Abdul Khader, Al-Attas Omar S, Ansari Mohammed Ghouse Ahmed, Wani Kaiser, Hussain Syed D, Sabico Shaun, Tripathi Gyanendra, Alokail Majed S
Abstract excerpt
There is conflicting evidence on the favorable effects of vitamin D supplementation on metabolic profile in Type 2 diabetes mellitus (T2DM) patients and this might be due to genetic variations in vitamin D receptors (VDRs). Thus, we studied the metabolic effects of a 12-month vitamin D supplementation in T2DM patients according to VDR polymorphisms. A total of 204 T2DM subjects received 2000 IU vitamin D3 daily...
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