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Article

Proneness to infections and familial risk of tic disorders.

Psychological medicine - 22 Apr 2026

Pol-Fuster Josep, Vasiljevic Sara, Fernández de la Cruz Lorena, Beucke Jan C, Hesselmark Eva, Crowley James J, Brikell Isabell, de Schipper Elles, D'Onofrio Brian M, Chang Zheng, Larsson Henrik, Tedroff Kristina, Lichtenstein Paul, Kuja-Halkola Ralf, Idring Selma, Mataix-Cols David

Abstract excerpt

BACKGROUND: Postinfectious autoimmune processes are hypothesized to be causally implicated in tic disorders, including Tourette syndrome and chronic tic disorder. However, this hypothesis remains controversial. In this nationwide cohort study, we aimed to clarify the mechanisms underlying the association between proneness to infections and tic disorders. METHODS: Using Swedish national registers, we identified...

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Identifiers

PMID: 42015626
DOI: 10.1017/S003329172610419X
PMCID: PMC13112282

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