Article
Infection Polygenic Factors Account for a Small Proportion of the Relationship Between Infections and Mental Disorders.
Biological psychiatry - 15 Aug 2022
Shorter John R, Meijsen Joeri, Nudel Ron, Krebs Morten, Gådin Jesper, Mikkelsen Dorte H, Nogueira Avelar E Silva Raquel, Benros Michael E, Thompson Wesley K, Ingason Andrés, Werge Thomas
Abstract excerpt
BACKGROUND: Several recent studies have suggested a role for infections in the development of mental disorders; however, the genetic contribution to this association is understudied. METHODS: We use the iPSYCH case-cohort genotyped sample (n = 65,534) and Danish health care registry data to study the genetic association between infections and mental disorders. To test the hypothesis that these associations are...
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