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Article

Genetic risk score constructed with common genetic variants in GCKR, FADS1, BCO1, and FGF21 is associated with lipid profile in Mexican adults.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Aug 2026

Jiménez-Ortega Rogelio Frank, López-Pérez Tania Valentina, Aparicio-Bautista Diana Ivette, Becerra-Cervera Adriana, Patiño Nelly, Aquino-Gálvez Arnoldo, Hidalgo-Bravo Alberto, Salmerón Jorge, Rivera-Paredez Berenice, Velázquez-Cruz Rafael

Abstract excerpt

BACKGROUND AND AIMS: Previous studies have reported that genetic variants in the GCKR, FADS1, BCO1, and FGF21 genes are associated with lipid metabolism and may contribute to the development of dyslipidemia (DL). In this study, we aimed to explore the relationship between single-nucleotide variants (SNVs) rs780094/rs1260326-GCKR, rs174546-FADS1, rs6564851-BCO1, and rs838133-FGF21 and the lipid profile, as a...

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Source

Identifiers

PMID: 42000248
DOI: 10.1016/j.numecd.2026.104707

Genes

BCO1
FADS1
FGF21
GCKR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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