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Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections

11 Jul 2022

Abstract excerpt

BACKGROUND: Antimicrobial resistance (AMR) is rising at an alarming rate and complicating the management of infectious diseases including lower respiratory tract infections (LRTI). Metagenomic next-generation sequencing (mNGS) is a recently established method for culture-independent LRTI diagnosis, but its utility for predicting AMR has remained unclear. We aimed to assess the performance of mNGS for AMR...

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PMID: 35818068
DOI: 10.1186/s13073-022-01072-4

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