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Article

Reduced COVID-19 severity in Africa: a systematic review of host genetic and immunological responses to SARS-CoV-2 infection.

Frontiers in immunology - 1 Jan 2026

Manu Gloria Pokuaa, Bonney Joseph H K, Bawa Flavia Kaduni, Quashie Peter Kojo, Kusi Kwadwo Asamoah, Amoah Linda Eva

Abstract excerpt

Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had immense global consequences, leading to widespread illness, deaths, and devastated economies. Despite this, Africa has experienced a high prevalence of asymptomatic coronavirus disease 2019 (COVID-19) and mild cases. While reported cases and deaths have been lower, limited testing and undiagnosed infections make it...

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Identifiers

PMID: 41993206
DOI: 10.3389/fimmu.2026.1782808
PMCID: PMC13079709

Genes

ACE2
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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