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Article

MELGene: knowledge-enhanced multimodel ensemble learning for disease-gene association prediction.

Briefings in bioinformatics - 1 Mar 2026

Tian Haoyu, Yang Kuo, Liu Zeyu, Gao Hong, Yu Jian, Zhang Lei, Zhou Xuezhong

Abstract excerpt

Disease-gene prediction (DGP) plays a pivotal role in understanding the genetic underpinnings of various diseases, offering insights for disease diagnosis, treatment, and prevention. Accurate identification of disease-related genes can enhance personalized medicine and the development of targeted therapies. While numerous methods for DGP have been proposed in the field, a significant challenge remains in...

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PMID: 41985062
DOI: 10.1093/bib/bbag172
PMCID: PMC13082380

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