Article
The gene mutation pattern of urachal squamous cell carcinoma resembles that of gastrointestinal tumors: a rare case with favorable prognosis following surgery and adjuvant chemotherapy.
World journal of surgical oncology - 10 Apr 2026
Lu Xiaochun, You Xiangyun, Liu Tao, Wei Yanan, Sun Deming, Yi Cheng, Li Tan, Yu Junfeng, Chen Xiaobo, Xiang Zhendong
Abstract excerpt
BACKGROUND: Urachal carcinoma (UrC) is a rare epithelial malignant tumor of the urinary system, with an age-standardized incidence of 0.32 per million population, accounting for 0.35–0.70% of all bladder tumors. Adenocarcinoma is the most common histological subtype of UrC, while squamous cell carcinoma is extremely rare, representing only 2% of all UrC cases, and is associated with a high mortality rate. Due to...
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