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Article

Association of single nucleotide polymorphisms in FILIP1-SENP6 and FTO with temporomandibular joint osteoarthritis: clinical and in silico study.

Scientific reports - 10 Apr 2026

Ono Emi, Takaoka Ryota, Kuyama Kotaro, Ono Masayuki, Ueda You, Morika Shion, Yamamoto Rie, Yatani Hirofumi, Ishigaki Shoichi, Kato Takafumi, Uchiyama Yuka, Shimamoto Hiroaki, Nishimura Masahiro

Abstract excerpt

This study investigated the association between temporomandibular joint osteoarthritis and specific single-nucleotide polymorphisms. We also explored the potential functional impacts of these polymorphisms using in silico methods. 354 patients with temporomandibular disorders were classified into osteoarthritis and without osteoarthritis according to the presence of degenerative bone changes in the magnetic...

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Source

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Identifiers

PMID: 41963434
DOI: 10.1038/s41598-026-47515-5
PMCID: PMC13243591

Genes

FILIP1
FTO
SENP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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