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Article

Dual TP53 mutations in ovarian high-grade serous carcinoma combined with squamous cell carcinoma: a case report and systematic literature review.

Journal of ovarian research - 9 Apr 2026

Li Chao-Lian, Lu Jie-Ping, Lan Qiu-Xing, Li Li, Lu Sha-Sha, Chen Zhi-Kai, Shi Jing, He Qing, Hou Peng, Dai Wen-Bin, Tan Yang

Abstract excerpt

OBJECTIVE: This study reports a rare case of mixed ovarian carcinoma composed of squamous cell carcinoma (SCC) and high-grade serous carcinoma (HGSC) arising from endometriosis, and provides a systematic review of the relevant literature. CASE PRESENTATION: A 59-year-old female presented with bilateral ovarian cystic lesions (4.6 cm on the left, 9.6 cm on the right) and a mural nodule in the right ovarian cyst....

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Share to Carcinoma, Squamous Cell
Share to Cystadenocarcinoma, Serous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TP53 gene

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Share to Neoplasm Grading

Share to Ovarian Neoplasms

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 41957787
DOI: 10.1186/s13048-026-02088-9
PMCID: PMC13192170

Genes

TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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