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Article

Characteristics of Mycobacterial, COVID-19, and Talaromyces Marneffei Infections in Patients with IL12RB1 and IFNGR1 Mutations in Western China.

Journal of clinical immunology - 10 Apr 2026

Zhang Wenjing, Zhang Zhenzhen, Liu Cong, Yang Xi, Tang Wenjing, Xing Shubin, Chen Ran, Tang Xuemei, Zhang Zhiyong, Ding Yuan, Zhou Lina, Jia Yanjun, An Yunfei, Zhao Xiaodong

Abstract excerpt

BACKGROUND: Mendelian susceptibility to mycobacterial disease (MSMD) is a rare immunodeficiency characterized by increased vulnerability to weakly virulent mycobacteria. However, its clinical and molecular spectrum, as well as its susceptibility to infections beyond mycobacteria, remains incompletely understood. OBJECTIVE: To evaluate the clinical and genetic characteristics of MSMD patients, focusing on their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41957131
DOI: 10.1007/s10875-026-01991-6
PMCID: PMC13246923

Genes

IFNGR1
IL12RB1
AR
NTM
STAT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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