Article
Identification of vital sign trajectory phenotypes and treatment response heterogeneity in critically ill patients with ischemic stroke: A multicenter study with external validation.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics - 1 Apr 2026
Wang Lijuan, Wang Duozi, Tang Bo, Duan Jun, Huang Jie
Abstract excerpt
Critically ill patients with ischemic stroke exhibit heterogeneous hemodynamic patterns, yet previous trajectory-based studies have focused on single vital sign parameters. We conducted a multicenter retrospective cohort study to identify vital sign trajectory phenotypes, evaluate their prognostic value compared with traditional severity scores, and explore treatment response heterogeneity. Using group-based...
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