Associations of excessive sleepiness with sleep apnea physiological endo-phenotypes: the multi-ethnic study of atherosclerosis.

doi:10.1093/annalsats/aaoag078

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Associations of excessive sleepiness with sleep apnea physiological endo-phenotypes: the multi-ethnic study of atherosclerosis.

Annals of the American Thoracic Society - 1 Jul 2026

Castro-Diehl Cecilia, Alex Raichel, Azarbarzin Ali, Zhang Ying, Wellman Andrew, Huang Tianyi, Sands Scott, Redline Susan

Abstract excerpt

BACKGROUND: Obstructive sleep apnea (OSA) is a heterogenous disease characterized by several endo-phenotypes (mechanistic traits and physiological severity metrics) and variable associations with excessive daytime sleepiness (EDS). Examining the relationship of EDS with features of OSA may identify physiological processes that drive increased risk for adverse health outcomes in patients with OSA and EDS. RESEARCH...

Topics

Humans
Female
Male
Aged
Polysomnography
Sleep Apnea, Obstructive
Disorders of Excessive Somnolence
Middle Aged
Phenotype
United States
Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Surveys and Questionnaires

Actigraphy

Severity of Illness Index

Hypoxia

Aged, 80 and over

Sleep Apnea Syndromes

Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41955419
DOI: 10.1093/annalsats/aaoag078
PMCID: PMC13315775

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-41955419-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of excessive sleepiness with sleep apnea physiological endo-phenotypes: the multi-ethnic study of atherosclerosis.PMID 41955419Read ↗

Sex differences in obstructive sleep apnea phenotypes, the multi-ethnic study of atherosclerosis.Semantic proximity Read ↗

Research Priorities for Translating Endophenotyping of Adult Obstructive Sleep Apnea to the Clinic: An Official American Thoracic Society Research Statement.Semantic proximity Read ↗

Differences in Endotypic Traits Between Obstructive Sleep Apnoea Patients With and Without Excessive Daytime Sleepiness.Semantic proximity Read ↗

The Different Clinical Faces of Obstructive Sleep Apnea (OSA), OSA in Older Adults as a Distinctly Different Physiological Phenotype, and the Impact of OSA on Cardiovascular Events after Coronary Artery Bypass Surgery.Semantic proximity Read ↗

Endotypes and phenotypes in obstructive sleep apnea.Semantic proximity Read ↗

Sex-specific age-related worsening of pathological endotypic traits in patients with obstructive sleep apnea.Semantic proximity Read ↗

Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea.Semantic proximity Read ↗

Genetic determinants of cardiometabolic and pulmonary phenotypes and obstructive sleep apnoea in HCHS/SOL.Semantic proximity Read ↗

Phenotypes in obstructive sleep apnea: A definition, examples and evolution of approaches.Semantic proximity Read ↗

Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea SubtypeSemantic proximity Read ↗

Sleep apnoea phenotypes in women: A cluster analysis from the ESADA cohort.Semantic proximity Read ↗

Cluster analysis of clinical phenotypic heterogeneity in obstructive sleep apnea assessed using photoplethysmography.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.