Association of a High Cardiovascular Disease Risk OSA Phenotype With Incident Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.

doi:10.1016/j.chest.2026.01.027

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Article

Association of a High Cardiovascular Disease Risk OSA Phenotype With Incident Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.

Chest - 1 Sept 2026

Xu Jing, Kwon Younghoon, Esmaeili Neda, Sands Scott A, Hajipour Mohammadreza, Vena Daniel, Heckbert Susan R, Soliman Elsayed Z, Wellman Andrew, Michos Erin D, Gottlieb Daniel J, Redline Susan, Azarbarzin Ali

Abstract excerpt

BACKGROUND: OSA is associated with atrial fibrillation (AF), but this association varies by population and definitions of OSA and AF. RESEARCH QUESTION: Is high cardiovascular disease risk (High-CVD-Risk) OSA, defined by elevated hypoxic burden (HB) or heart rate response to respiratory events (ΔHR), associated with incident AF? STUDY DESIGN AND METHODS: Using data from the Multi-Ethnic Study of Atherosclerosis,...

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Topics

Humans
Atrial Fibrillation
Female
Male
Sleep Apnea, Obstructive

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Incidence

Aged

Phenotype

Middle Aged

Atherosclerosis

United States

Heart Rate

Risk Factors

Hypoxia

Proportional Hazards Models

Risk Assessment

Heart Disease Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41794120
DOI: 10.1016/j.chest.2026.01.027
PMCID: PMC13220130

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