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Article

From colonization to invasion: genomic and phenotypic comparison of faecal and bloodstream isolates from the same patients.

Journal of medical microbiology - 1 Apr 2026

Khanijau Aakash, Allman Ellie, Pulmones Ralfh, Goodman Richard N, Cantillon Daire, McGalliard Rachel, Parry Christopher M, Carrol Enitan D, Roberts Adam P

Abstract excerpt

Introduction. Gram-negative bloodstream infections (GNBSIs) carry a significant global health burden. Escherichia coli and Klebsiella pneumoniae are the two most common causes of healthcare-associated GNBSI, which may arise from gastrointestinal tract (GIT) colonization.Gap Statement. We do not fully understand how GNBSIs arise from GIT colonization.Aim. To understand E. coli and K. pneumoniae genomic and...

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Identifiers

PMID: 41950070
DOI: 10.1099/jmm.0.002147
PMCID: PMC13061263

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