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Article

Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jul 2017

Gorrie Claire L, Mirceta Mirjana, Wick Ryan R, Edwards David J, Thomson Nicholas R, Strugnell Richard A, Pratt Nigel F, Garlick Jill S, Watson Kerri M, Pilcher David V, McGloughlin Steve A, Spelman Denis W, Jenney Adam W J, Holt Kathryn E

Abstract excerpt

BACKGROUND: Klebsiella pneumoniae is an opportunistic pathogen and leading cause of hospital-associated infections. Intensive care unit (ICU) patients are particularly at risk. Klebsiella pneumoniae is part of the healthy human microbiome, providing a potential reservoir for infection. However, the frequency of gut colonization and its contribution to infections are not well characterized. METHODS: We conducted a...

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Identifiers

PMID: 28369261
DOI: 10.1093/cid/cix270
PMCID: PMC5850561

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