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Article

The "Asian Paradox" in multiple primary lung cancer: a geographic monopole driven by phenotypic divergence.

NPJ primary care respiratory medicine - 6 Apr 2026

Shi Jianwei, Gao Yushun

Abstract excerpt

The global clinical trial landscape for multiple primary lung cancer (MPLC) exhibits a striking geographic anomaly. Through a systematic analysis of 8212 lung cancer registrations (2015-2024), we identified a cohort of 17 trials explicitly targeting MPLC. Analysis revealed an absolute geographic monopole: 100% of these trials were investigator-initiated in China, with a complete absence of active protocols in...

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Identifiers

PMID: 41942506
DOI: 10.1038/s41533-026-00504-7
PMCID: PMC13053711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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