Article
Polymorphisms in the LMP1 gene in patients with gastric cancer associated with Epstein-Barr virus (Orthoherpesviridae: Gammaherpesvirinae: Lymphocryptovirus: Lymphocryptovirus humangamma 4).
Voprosy virusologii - 28 Feb 2026
Vasilyeva A S, Margusheva A A, Molchanov A D, Rtishchev A A, Cherepovich B S, Domanskaya V A, Gurtsevich V E, Smirnova K V
Abstract excerpt
INTRODUCTION: Epstein-Barr virus (EBV) is a widespread gamma-herpesvirus associated with a number of malignancies, including nasopharyngeal carcinoma and gastric cancer (GC/EBV+). The primary oncogenic protein of EBV is latent membrane protein 1 (LMP1). Genetic variability of the LMP1 protein affects its oncogenic activity and clinical manifestations. OBJECTIVE: To investigate the optimal threshold value for EBV...
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