Article
Genomic Landscape and Clinical Outcomes of Advanced Pediatric Myelodysplastic Syndromes.
European journal of haematology - 1 Jul 2026
Liu Chenmeng, Wang Xingchen, Chen Yunlong, Wan Yang, An Wenbin, Li Xiaolan, Liu Lipeng, Liu Fang, Zhang Li, Zou Yao, Chen Xiaojuan, Chen Yumei, Guo Ye, Yang Wenyu, Zhu Xiaofan
Abstract excerpt
OBJECTIVES: Pediatric myelodysplastic syndromes (MDS) differ from adult MDS, and their genetic basis is poorly understood. This study characterizes the genomic features and clinical outcomes of advanced pediatric MDS. METHODS: In this retrospective study, next-generation sequencing was performed on 63 pediatric patients with advanced MDS, including 46 with MDS with excess blasts (MDS-EB) and 17 with MDS-EB in...
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