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Cooley's Legacy Endures-Elliptocytes in X-Linked Sideroblastic Anemia Due to Aminolevulinate Synthase 2 Mutations.

Pediatric blood & cancer - 1 Jun 2026

Ciurej Alex, Savaşan Süreyya, Bhambhani Kanta, Gadgeel Manisha, Rajpurkar Madhvi, Ravindranath Yaddanapudi

Abstract excerpt

X-linked sideroblastic anemia (XLSA) is categorized as hypochromic microcytic anemia. In 3 children with XLSA, we observed prominent elliptocytosis, and red cell band 3 content histograms were similar to those found in hereditary elliptocytosis, thus validating Cooley's descriptions in 1945.

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Share to 5-Aminolevulinate Synthetase
Share to Anemia, Sideroblastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Elliptocytosis, Hereditary

Share to Erythrocytes, Abnormal

Share to Genetic Diseases, X-Linked

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Source

Identifiers

PMID: 41925069
DOI: 10.1002/1545-5017.70313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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