Article
Forward genetic screening of mutants of the wild diploid ancestor Nicotiana sylvestris identifies aspartate oxidase 2 as a key gene for nicotine biosynthesis in cultivated allotetraploid tobacco (Nicotiana tabacum).
The Plant journal : for cell and molecular biology - 1 Apr 2026
Takeuchi Takanori, Udagawa Hisashi, Arai Masao, Nishiguchi Ryo, Yoshikiyo Tsubasa, Tajima Tomoyuki, Magome Hiroshi, Takakura Yoshimitsu
Abstract excerpt
Tobacco (Nicotiana tabacum) is one of the most important commercial crops. It is an allotetraploid with two subgenomes derived from two wild diploid species: the maternal ancestor Nicotiana sylvestris and the paternal ancestor Nicotiana tomentosiformis. The functional duplication of homologous genes derived from both subgenomes often hinders phenotypic screening because a recessive mutation on one homeolog is...
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