Field performance, alkaloid quantities, and transcriptome profiles of nearly isogenic tobacco lines possessing alternative allelic combinations at the Nic1, Nic2, and Myc2a loci.

Abstract excerpt

Tobacco with modified genetics controlling alkaloid accumulation has been of interest because of the possibility of mandated lowering of nicotine levels in combustible cigarettes by regulatory authorities. Transcription factors coded by the Nic1, Nic2, and Myc2a loci act as positive regulators of genes directly involved in alkaloid accumulation. In this research, different combinations of alternative alleles at...

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