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Current Status and the Need for CFTR Modulator Therapy in Cystic Fibrosis Patients in Mainland China: A Case Report and Literature Review.

Pediatric pulmonology - 1 Apr 2026

Sun Yuxiao, Du Junbao, Gong Lifen, Wang Jialiang, Zhang Jing, Xu Yaqin, Wang Lei, Zhang Ziwei, Cheng Hang

Abstract excerpt

BACKGROUND: Cystic fibrosis (CF) is a life-threatening genetic disorder characterized by dysfunctional mucus production, leading to severe respiratory and digestive complications. CF transmembrane conductance regulator (CFTR) modulators are highly effective targeted therapies for CF; however, they are not yet available in mainland China, resulting in no published reports on their use in Chinese CF patients....

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Identifiers

PMID: 41918264
DOI: 10.1002/ppul.71590

Genes

CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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