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Article

GRIN2A: one gene, many phenotypes.

Trends in genetics : TIG - 1 Apr 2026

Singh Tarjinder

Abstract excerpt

GRIN2A, a gene encoding a subunit of the N-methyl-d-aspartate (NMDA) receptor, is linked to epilepsy, language impairment, and schizophrenia, but how these associations relate to one another within individuals remains unclear. Recontacting GRIN2A carriers shows that loss-of-function variants are associated with psychiatric risk not captured in earlier ascertainment of the same cohort, highlighting how study...

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Source

Identifiers

PMID: 41876267
DOI: 10.1016/j.tig.2026.02.004

Genes

GRIN2A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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