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Molecular epidemiology and structural diversity of O101/O162 O-antigen variants among Escherichia coli bacteremia isolates.

Scientific reports - 23 Mar 2026

Weerdenburg Eveline, de Been Mark, Zomer Aldert, Ritmahan Wannisa, Lübbers Joyce, Moran Alan B, Nicolardi Simone, Wuhrer Manfred, Ravenscroft Neil, Anish Chakkumkal, Geurtsen Jeroen, Beurret Michel

Abstract excerpt

Most human invasive infections caused by extraintestinal pathogenic Escherichia coli (ExPEC) are associated with a limited number of O-serotypes and O-serogroups, including O101/O162. Here, we examined E. coli O101/O162 O-serogroup epidemiology among bacteremia isolates and performed genetic, biochemical and structural analyses. We demonstrate that the O101/O162 O-serogroup is globally widespread and highly...

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PMID: 41872483
DOI: 10.1038/s41598-026-45688-7

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