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Genomic evolution of SARS-CoV-2 delta variants pre- and post-omicron emergence using alignment-free machine learning models.

PloS one - 1 Jan 2026

Sankar Sathish, Anandharaman Kaushika, Selvam Pradeesh, Jayaraman Aswini, Jayakumar Deepak, Balakrishnan Pachamuthu, Larsson Marie, Velu Vijayakumar, Raju Sivadoss, Shankar Esaki M

Abstract excerpt

The SARS-CoV-2 Delta variant (B.1.617.2), initially classified as a variant of concern due to its enhanced transmissibility and vaccine-escape mutations, underwent further genomic changes following the emergence of the Omicron variant (B.1.1.529). This study investigates the genomic differences in Delta variant spike gene sequences collected before and after the emergence of Omicron. A total of 190 sequences were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41855150
DOI: 10.1371/journal.pone.0345259
PMCID: PMC13001964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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