Article
Mining whole-brain information with deep learning to predict EGFR mutation and subtypes in brain-metastatic NSCLC: A multicenter study.
Medical physics - 1 Mar 2026
You Shuailin, Fan Ying, Zhang Jin, Yang Chunna, Sun Yiyao, Jiang Mingchen, Chen Huanhuan, Guo Wei, Yang Hong, Jiang Wenyan
Abstract excerpt
BACKGROUND: Epidermal growth factor receptor (EGFR) and its mutation subtypes play a pivotal role in the treatment of non-small cell lung cancer (NSCLC) patients. Therefore, developing an accurate, noninvasive quantitative method to predict EGFR genotype is crucial for personalized treatment. PURPOSE: To explore a deep learning-based method with whole-brain information for predicting EGFR mutation and subtypes...
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