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Article

Predicting EGFR mutation status by a deep learning approach in patients with non-small cell lung cancer brain metastases.

Journal of neuro-oncology - 1 Mar 2022

Haim Oz, Abramov Shani, Shofty Ben, Fanizzi Claudia, DiMeco Francesco, Avisdris Netanell, Ram Zvi, Artzi Moran, Grossman Rachel

Abstract excerpt

PURPOSE: Non-small cell lung cancer (NSCLC) tends to metastasize to the brain. Between 10 and 60% of NSCLCs harbor an activating mutation in the epidermal growth-factor receptor (EGFR), which may be targeted with selective EGFR inhibitors. However, due to a high discordance rate between the molecular profile of the primary tumor and the brain metastases (BMs), identifying an individual patient's EGFR status of...

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PMID: 35119589
DOI: 10.1007/s11060-022-03946-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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