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Article

Association of circadian rhythms, MTNR1B, BMAL1, BMAL2, and CRY2 gene polymorphisms and their interactions with type 2 diabetes in coal miners.

Frontiers in endocrinology - 1 Jan 2026

Li Qinglin, Cao Haoyue, Zhang Xiaohong, Yuan Juxiang, Zhang Chunze

Abstract excerpt

Objective: To investigate the interaction between circadian rhythm disorders and related gene polymorphisms (SNPs) in the risk of developing type 2 diabetes (T2DM). Methods: Cross-sectional study included 4,070 coal miners who underwent occupational health examinations between 2017 and 2018. We constructed comprehensive indicators of circadian rhythm disorder (CICRD) using factor analysis. In case-control...

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Source

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Identifiers

PMID: 41847453
DOI: 10.3389/fendo.2026.1567465
PMCID: PMC12989341

Genes

BMAL2
CRY2
MTNR1B
BMAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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