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Diverse and rare candidate MODY gene variants were identified in one-fifth of a Bangladeshi cohort with nonobese, nonautoimmune youth-onset diabetes.

Scientific reports - 17 Mar 2026

Hasan Mashfiqul, Sultana Nusrat, Shil Kishore Kumar, Abdus-Salam Sayad Bin, Nayem Maksudur Rahman, Oliver Merina, Padinjyarekara Aswathi, Golani Tamanna, Rabbi Mohammad Fazle Alam, Salimullah Md, Akhteruzzaman Sharif, Hasanat Muhammad Abul

Abstract excerpt

The global distribution and frequency of maturity onset diabetes of the young (MODY) vary, necessitating investigation across diverse ethnic groups. This study aimed to investigate MODY gene variants and phenotypic characteristics among young Bangladeshi individuals with nonobese, nonautoimmune youth-onset diabetes. Fifty participants with diabetes (onset < 35 years, BMI < 25 kg/m², negative for islet...

Topics

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Bangladesh
Basic Helix-Loop-Helix Proteins
Hepatocyte Nuclear Factor 1-alpha
Homeodomain Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Paired Box Transcription Factors

Potassium Channels, Inwardly Rectifying

Sulfonylurea Receptors

Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 41844744
DOI: 10.1038/s41598-026-43760-w
PMCID: PMC13128926

Genes

ABCC8
BLK
HNF1A
KCNJ11
KLF11
NEUROD1
PAX4
PDX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Diverse and rare candidate MODY gene variants were identified in one-fifth of a Bangladeshi cohort with nonobese, nonautoimmune youth-onset diabetes.PMID 41844744Read ↗

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