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Article

Risk of Cancer in Patients With Primary Sjögren's Disease and Their Relatives.

International journal of rheumatic diseases - 1 Mar 2026

Tuzcu Tuba Uğur, Karaduman İbrahim, Kardaş Rıza Can, Erden Abdulsamet, Küçük Hamit, Öztürk Mehmet Akif, Göker Berna

Abstract excerpt

OBJECTIVES: Familial clustering and HLA haplotype association studies suggest that genetic factors disrupting the regulation of the immune system may predispose to risk of both neoplasms and autoimmune diseases, potentially leading to an increased frequency of cancer development in patients with primary Sjögren's disease (SjD), as well as their relatives. In this study, we aimed to assess the risk of cancer in...

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PMID: 41841201
DOI: 10.1111/1756-185x.70613

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