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Article

Anisotropic Cellular Forces Drive Hexagonal-to-Tetragonal Tiling Transitions in the Drosophila Eye.

Development, growth & differentiation - 1 Apr 2026

Zheng Ting, Davis Steven R, Li Cuicui, Ren Weichao, Sato Makoto

Abstract excerpt

Tile patterns are fundamental organizational principles of multicellular epithelial tissues. The Drosophila compound eye provides a striking example, in which ommatidia are arranged in a highly regular hexagonal lattice, while tetragonal patterns emerge in specific small-eye mutants. Although increased dorsoventral tension has been implicated in this hexagonal-to-tetragonal transition, conventional vertex models...

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PMID: 41805025
DOI: 10.1111/dgd.70050
PMCID: PMC13017196

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