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Article

Epicardial adipose tissue as a determinant of heart failure prognosis: insights across ejection fraction phenotypes.

Cardiovascular diabetology - 9 Mar 2026

Nowakowski Maksymilian, Mazuruk Maciej, Nogajski Łukasz, Mączewski Maciej, Czerwińska Hanna, Kurpias Mikołaj, Mączewski Michał, Paterek Aleksandra

Abstract excerpt

Epicardial adipose tissue (EAT) is a metabolically active fat depot located between the myocardium and visceral pericardium, directly interacting with cardiomyocytes and coronary vasculature. Emerging evidence suggests that EAT plays a significant role in the pathophysiology and prognosis of heart failure (HF) across different left ventricular ejection fraction (LVEF) phenotypes. This review summarizes current...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41803855
DOI: 10.1186/s12933-026-03126-y
PMCID: PMC13020216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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