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Article

Validation of molecular classification on diagnostic biopsy in endometrial carcinoma: the first step for a tailored approach.

Journal of gynecologic oncology - 1 Jul 2026

Spagnol Giulia, Marchetti Matteo, Vezzaro Tommaso, Panizzolo Eleonora, Bigardi Sofia, De Tommasi Orazio, Guerriero Angela, Alessandrini Lara, Noventa Marco, Tozzi Roberto, Saccardi Carlo

Abstract excerpt

OBJECTIVE: To validate the concordance of histologic subtype, tumor grade, molecular classification, and risk group between pre-operative endometrial biopsy and final hysterectomy specimens in patients with endometrial cancer (EC). METHODS: The PReOperative MOlecular Biopsy (ProMobi) study is a prospective, monocentric, observational study conducted from September 2023 to March 2024. All patients with suspicious...

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Identifiers

PMID: 41796991
DOI: 10.3802/jgo.2026.37.e67
PMCID: PMC13365767

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