Article
Prediction of molecular subtypes for endometrial cancer based on hierarchical foundation model.
Bioinformatics (Oxford, England) - 4 Feb 2025
Cui Haoyu, Guo Qinhao, Xu Jun, Wu Xiaohua, Cai Chengfei, Jiao Yiping, Ming Wenlong, Wen Hao, Wang Xiangxue
Abstract excerpt
MOTIVATION: Endometrial cancer is a prevalent gynecological malignancy that requires accurate identification of its molecular subtypes for effective diagnosis and treatment. Four molecular subtypes with different clinical outcomes have been identified: POLE mutation, mismatch repair deficient, p53 abnormal, and no specific molecular profile. However, determining these subtypes typically relies on expensive gene...
Read the complete abstract on PubMedTopics
- Humans
- Endometrial Neoplasms
- Female
- Computational Biology
- Algorithms
- Mutation