Article
Family history of stroke and cardiovascular diseases in early-onset cryptogenic ischaemic stroke.
European stroke journal - 1 Mar 2026
Sihvo Maximilian C, Ylikotila Pauli, Zedde Marialuisa, Pascarella Rosario, Sarkanen Tomi, Jatužis Dalius, Ryliškienė Kristina, von Sarnowski Bettina, Licenik Radim, Ferdinand Phillip, Kõrv Janika, Kõrv Liisa, Pezzini Alessandro, Fonseca Ana Catarina, Paula André, Martínez-Sánchez Patricia, Yesilot Nilufer, Fromm Annette, Waje-Andreassen Ulrike, Redfors Petra, Jood Katarina, Huhtakangas Juha, Sairanen Tiina, Hedman Marja, Jäkälä Pekka, Ten Cate Hugo, Gerdts Eva, Lehto Mika, Sinisalo Juha, Kittner Steven J, Mitchell Braxton D, Lindgren Arne G, Ilinca Andreea, Putaala Jukka, Tomppo Liisa
Abstract excerpt
BACKGROUND: Familial aggregation of stroke is well-documented, yet few studies have examined associations between stroke subtypes-particularly early-onset cryptogenic ischaemic stroke (eCIS)-and broader family history (FH) of cardiovascular disease. Such associations may provide insights into underlying etiologic mechanisms. METHODS: In this multicentre case-control study, we included eCIS patients aged 18-49...
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