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A review of family history of cardiovascular disease: risk factor and research tool

18 May 2012

Abstract excerpt

Family history (FH) studies have been used to quantify the heritable component of diseases for centuries. Genome-wide association studies (GWAS) in both coronary artery disease (CAD) and stroke have implicated several gene loci in these diseases and have shed light on biological mechanisms, but have not yet yielded fruit in terms of clinical application, partly because of the complexity of gene-gene and...

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PMID: 22607505
DOI: 10.1111/j.1742-1241.2012.02908.x

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