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Simultaneous detection of Mycobacterium tuberculosis complex and rifampin/isoniazid resistance with sanity 2.0 MTBC-MDR: a moderate-complexity automated NAAT.

World journal of microbiology & biotechnology - 6 Mar 2026

Ou Xichao, Zhao Bing, Xia Hui, Bao Xundi, Xu Dongfang, Ma Qi, Xu Ye, Li Jingjing, Shi Wenzhi, Li Feina, Guo Yajie, Xing Ruida, Zhao Yanlin, Zheng Huiwen

Abstract excerpt

OBJECTIVE: To compare the performance of Sanity 2.0 with that of Xpert MTB/RIF and phenotypic drug susceptibility testing (DST) for the detection of Mycobacterium tuberculosis complex (MTBC) and resistance to rifampicin (RIF) and isoniazid (INH). METHODS: Acid-fast staining positive sputum samples, collected from February to July in 2024, were used for solid culture, DST, Xpert MTB/RIF, and Sanity 2.0 assay....

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PMID: 41790160
DOI: 10.1007/s11274-026-04858-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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