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XtracTB Assay, a Mycobacterium tuberculosis molecular screening test with sensitivity approaching culture

12 Jun 2017

Abstract excerpt

Nucleic acid amplification tests are increasingly used to diagnose tuberculosis (TB) due to their speed and sensitivity compared to sputum smear microscopy. However, these tests fail to equal culture's sensitivity with sputum smear microscopy negative specimens and therefore cannot be used to rule out TB disease. For molecular tests to match culture's sensitivity, they must detect ≤10 genomic copies of...

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PMID: 28623303
DOI: 10.1038/s41598-017-03930-3

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