Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Within-host adaptation mutations associated with persistent colonization of Pseudomonas aeruginosa in a silicosis patient.

Frontiers in cellular and infection microbiology - 1 Jan 2026

Zhang Furong, Qian Lvxin, Yan Yi, Wan Qiuling, Zhang Luhua, Li Ying

Abstract excerpt

Pseudomonas aeruginosa is a notorious opportunistic pathogen that causes life-threatening infections in immunocompromised individuals. In this study, we isolated two mucoid imipenem-resistant P. aeruginosa strains, SCPa14 and SCPa16, from a single silicosis patient. Whole-genome sequencing revealed that these two strains are homologous, both of which belong to the epidemic high-risk clone ST274. Gene sequence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biofilms
Share to Cathelicidins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen Peroxide

Share to Imipenem

Share to Porins

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 41782941
DOI: 10.3389/fcimb.2026.1739179
PMCID: PMC12953531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Within-host adaptation mutations associated with persistent colonization of Pseudomonas aeruginosa in a silicosis patient.PMID 41782941Read ↗

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence FactorsSemantic proximity Read ↗

Intrinsic and environmental mutagenesis drive diversification and persistence of Pseudomonas aeruginosa in chronic lung infections.Semantic proximity Read ↗

Biofilm Formation of Pseudomonas aeruginosa in Cystic Fibrosis: Mechanisms of Persistence, Adaptation, and PathogenesisSemantic proximity Read ↗

Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs—A ReviewSemantic proximity Read ↗

Pseudomonas aeruginosa infection and persistence mechanisms in cystic fibrosis patientsSemantic proximity Read ↗

Differential adaptation of microbial pathogens to airways of patients with cystic fibrosis and chronic obstructive pulmonary diseaseSemantic proximity Read ↗

Case report: Genotype analysis of a patient with bronchiectasis infected by a rare strain of Pseudomonas aeruginosaSemantic proximity Read ↗

Persistent Bacterial Coinfection of a COVID-19 Patient Caused by a Genetically Adapted Pseudomonas aeruginosa Chronic ColonizerSemantic proximity Read ↗

Cross-sectional analysis of clinical and environmental isolates of Pseudomonas aeruginosa: biofilm formation, virulence, and genome diversity.Semantic proximity Read ↗

Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments.Semantic proximity Read ↗

Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains.Semantic proximity Read ↗

Diversification of Pseudomonas aeruginosa within the cystic fibrosis lung and its effects on antibiotic resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.