Article
Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains.
BMC genomics - 30 Oct 2015
Varga John J, Barbier Mariette, Mulet Xavier, Bielecki Piotr, Bartell Jennifer A, Owings Joshua P, Martinez-Ramos Inmaculada, Hittle Lauren E, Davis Michael R, Damron F Heath, Liechti George W, Puchałka Jacek, dos Santos Vitor A P Martins, Ernst Robert K, Papin Jason A, Albertí Sebastian, Oliver Antonio, Goldberg Joanna B
Abstract excerpt
BACKGROUND: Pseudomonas aeruginosa is an environmentally ubiquitous Gram-negative bacterium and important opportunistic human pathogen, causing severe chronic respiratory infections in patients with underlying conditions such as cystic fibrosis (CF) or bronchiectasis. In order to identify mechanisms responsible for adaptation during bronchiectasis infections, a bronchiectasis isolate, PAHM4, was phenotypically...
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