Article
Frequent NPM1 mutation, monoblastic/monocytic origin and prognostic significance of organ and system involvement in myeloid sarcoma: a multicenter study.
The journal of pathology. Clinical research - 1 Mar 2026
Jenei Alex, Kajtár Béla, László Tamás, Juratli Hazem A, Vida Livia, Szepesi Ágota, Mózes Réka, Timár Botond, Halter Jörg, Dirnhofer Stefan, Tzankov Alexandar
Abstract excerpt
Myeloid sarcoma (MS) is a tumorous extramedullary proliferation of blast or blast equivalent cells (e.g., promonocytes or promyelocytes). The most frequent cutaneous presentation is often referred to as leukemia cutis (LC). These lesions, especially without the clinical context of a known bone marrow disease, pose a differential diagnostic challenge. In this retrospective multicenter clinico-pathological study on...
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