Article
Pretherapeutic prognostic factors for survival under chemoimmunotherapy/immunotherapy of advanced NSCLC patients.
European journal of cancer (Oxford, England : 1990) - 2 May 2026
Judickiene Julija, Metzenmacher Martin, Zaun Gregor, Wiesweg Marcel, Meschke Dorothea E, Guberina Nika, Oezkan Filiz, Hense Jörg, Schuler Martin, Theegarten Dirk, Bolükbas Servet, Stuschke Martin, Eberhardt Wilfried E E
Abstract excerpt
BACKGROUND: Checkpoint inhibitor therapy with PD-1/PD-L1-antibodies has significant benefits in non-small-cell lung cancer treatment even in advanced stage IVA/B. While PD-L1 expression in tumor is a weak but relevant predictor of treatment response, impact and interaction of potential prognostic factors like ECOG status, LDH-levels, CRP-levels, and genetic mutations remain so far undefined. This study aims to...
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