Article
Putative predictors of efficacy for immune checkpoint inhibitors in non-small-cell lung cancer: facing the complexity of the immune system.
Expert review of molecular diagnostics - 1 Dec 2017
Grizzi Giulia, Caccese Mario, Gkountakos Anastasios, Carbognin Luisa, Tortora Giampaolo, Bria Emilio, Pilotto Sara
Abstract excerpt
INTRODUCTION: In non-small-cell lung cancer (NSCLC) the recent introduction of immunotherapy in daily clinical practice produced a wave of enthusiasm, however, this was rapidly moderated by the evidence that only some patients could experience a relevant clinical benefit. Therefore, a great effort from the scientific community has been dedicated to the identification and validation of reliable biomarkers able to...
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