Article
Potent efficacy of an NA-targeting antibody against a broad spectrum of H5N1 influenza viruses.
Nature communications - 2 Mar 2026
Moriyama Saya, di Iulio Julia, Zatta Fabrizia, Hauser Kevin, Asanuma Hideki, Muñoz Hector E, Errico John M, Adachi Yu, Dang Ha V, Czudnochowski Nadine, Sasaki Eita, Chen Alex, Chen Yi-Pei, Kotaki Ryutaro, Peter Alessia, Vetti Eneida, Onodera Taishi, Cyrus Maher M, Rosen Laura E, Shirakura Masayuki, Snell Gyorgy, Hasegawa Hideki, Takahashi Yoshimasa, Corti Davide, Pizzuto Matteo Samuele
Abstract excerpt
For nearly 30 years, Goose/Guangdong-derived highly pathogenic avian influenza H5N1 viruses have posed significant risks to economic stability, food security, and public health. Virus evolution has resulted in various clades, including the panzootic subclade 2.3.4.4b, recognized for its pandemic potential. Here we present the potent in vitro activity of FNI9, a pan-influenza NA-inhibiting monoclonal antibody,...
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