Toxicity of polyethylene terephthalate and polylactic acid nanoplastics, pristine and weathered in environmentally-relevant conditions, to human intestinal cells representative of genetic susceptibility to Crohn's disease.

doi:10.1016/j.fct.2026.116027

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Toxicity of polyethylene terephthalate and polylactic acid nanoplastics, pristine and weathered in environmentally-relevant conditions, to human intestinal cells representative of genetic susceptibility to Crohn's disease.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jun 2026

Bard Vérane, Papin Margaux, Boulée Maeva, Berenguer Marion, Villacorta Aliro, Fenel Daphna, Dusacq Emma, Marcos Ricard, Hernández Alba, Sergent Jacques-Aurélien, Douki Thierry, Carriere Marie

Abstract excerpt

Environmental pollution by micro- and nanoplastics (MNPs) raises concerns about their toxicity to humans, particularly through ingestion. While the impact of native MNPs is increasingly documented, environmentally degraded MNPs remain poorly studied. We assessed the intestinal impact of biodegradable and non-biodegradable nanoplastics (NPLs), polyethylene terephthalate (PET) and poly-lactic acid (PLA), both...

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PMID: 41771477
DOI: 10.1016/j.fct.2026.116027

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