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Article

Hyperparathyroidism drives periodontitis progression via parathyroid hormone-induced endoplasmic reticulum stress.

Biochemical and biophysical research communications - 23 Apr 2026

Wang Huiyi, Wu Jing, Huang Zhendong, Yang Zhengkun, Ding Jiayi, Wang Xiaoxuan, Cao Zhengguo

Abstract excerpt

AIMS: Given the high prevalence of periodontitis and potential for undetected primary hyperparathyroidism (pHPT) to exacerbate periodontal damage, managing pHPT in advanced periodontitis (stages III/IV) is critical. The causal link between pHPT and periodontitis remains unclear. This study aims to investigate the causal effect and mechanisms between hyperparathyroidism and periodontitis. METHODS: A two-sample...

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Identifiers

PMID: 41771208
DOI: 10.1016/j.bbrc.2026.153512

Genes

PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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