Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 integrase resistance in the context of antiretroviral therapy in paediatric patients ‒ Northeast Brazil.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2026

Luz Aldicléya Lima, Leal Élcio, Lima Kledoaldo, Souza Mikhael Morais de, Silva Michelle Lima de Carvalho, Lima Mayra Moura, Sette Paloma Gomes Tavares, Almeida Yasmim Leandra Moura de, Melo Heloísa Ramos Lacerda de

Abstract excerpt

INTRODUCTION: Antiretroviral drug resistance poses a challenge to therapy efficacy. Although Integrase Strand Transfer Inhibitors (INSTIs) have a high genetic barrier to resistance, few studies in Brazil have focused on INSTI resistance. This study aimed to assess HIV mutations associated with INSTI resistance in vertically infected children in Maranhão and Pernambuco, Brazil. METHODS: We conducted a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to CD4 Lymphocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to HIV Infections

Share to HIV Integrase

Share to HIV Integrase Inhibitors

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 41764988
DOI: 10.1016/j.bjid.2026.105788
PMCID: PMC12966703

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 integrase resistance in the context of antiretroviral therapy in paediatric patients ‒ Northeast Brazil.PMID 41764988Read ↗

Resistance to integrase inhibitors in children with vertically-transmitted human immunodeficiency virus: First cases in Uruguay.Semantic proximity Read ↗

Overview of genotypic and clinical profiles of human immunodeficiency virus type 1-infected children in Rio de Janeiro, Brazil.Semantic proximity Read ↗

Drug resistance in the HIV-1-infected paediatric population worldwide: a systematic review.Semantic proximity Read ↗

Prevalence and risk factors associated with antiretroviral resistance in HIV-1-infected children.Semantic proximity Read ↗

HIV-1-resistance-associated mutations after failure of first-line antiretroviral treatment among children in resource-poor regions: a systematic review.Semantic proximity Read ↗

Trends in Drug Resistance Prevalence, HIV-1 Variants and Clinical Status in HIV-1-infected Pediatric Population in Madrid: 1993 to 2015 Analysis.Semantic proximity Read ↗

Drug resistance in children and adolescents with HIV in Panama.Semantic proximity Read ↗

Prevalence of transmitted HIV-1 drug resistance mutations in children and adolescents in São Paulo, Brazil.Semantic proximity Read ↗

HIV-1 subtypes and drug resistance in children during antiretroviral therapy in Brazil.Semantic proximity Read ↗

Trends in drug resistance prevalence in HIV-1-infected children in Madrid: 1993 to 2010 analysis.Semantic proximity Read ↗

Diversity and prevalence of antiretroviral genotypic resistance mutations among HIV-1-infected children.Semantic proximity Read ↗

HIV-1 Diversity and Drug Resistance in Treatment-Naïve Children and Adolescents from Rio de Janeiro, Brazil.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.