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Article

Radiogenomics in Leptomeningeal Metastasis of Lung Adenocarcinoma: MRI Patterns and Survival Outcomes Following Ommaya Reservoir Chemotherapy.

Journal of magnetic resonance imaging : JMRI - 1 Jul 2026

Jia Yi-Zhen, Zhong Yan, Shen Wen-Hui, Zhang Teng, Gao Wen, Fang Shen-Cun, Yuan Mei

Abstract excerpt

BACKGROUND: 10%-30% of patients with lung adenocarcinoma (LUAD) and leptomeningeal metastasis (LM) respond poorly to conventional and targeted therapy. The relationship between genetic subtypes and both MRI features and survival outcomes remains poorly understood in this patient population. PURPOSE: To explore the genetic phenotypes among LUAD-LM patients who respond poorly to conventional and targeted therapy,...

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PMID: 41761417
DOI: 10.1002/jmri.70280

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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