Article
Detection of HIV-1 Resistance Mutations to Antiretroviral Therapy and Cell Tropism in Russian Patients Using Next-Generation Sequencing.
Pathogens (Basel, Switzerland) - 28 Jan 2026
Fadeev Artem, Eder Veronika, Pisareva Maria, Tsvetkov Valery, Masharskiy Alexey, Komissarova Kseniya, Ivanova Anna, Yolshin Nikita, Komissarov Andrey, Mazus Alexey, Lioznov Dmitry
Abstract excerpt
The use of antiretroviral therapy (ART) as the only effective way to control human immunodeficiency virus (HIV) infection results in HIV drug resistance. Next-generation sequencing (NGS) has become a common method for identifying drug-resistant variants and reducing analysis costs. The aim of this study was to develop an NGS-based protocol for identifying resistance mutations and cell tropism of HIV-1 in adult...
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